Anti-ABCA1

• Description:

  Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

• Immunogen:

  Peptides amino acids 1800-2260 (C-Terminal end)

• Clonality:

  Monoclonal

• Clone:

  AB.H10

• Type:

  Antibodies-Monoclonal

• Applications:

  WB,IHC,ELISA,IP

• Concentration:

  100ug/100ul

• Buffer:

  PBS, pH 7.4 with 0.05% sodium azide.

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment:

  IgG

• Specificity:

  Recognize specifically ABCA1 from human, mouse, and chicken.

• CAS Number:

  9007-83-4