Methyl salvionolate A

Methyl salvionolate A

• CAS Number: 1015171-69-3
• UNSPSC Description: Methyl salvionolate A is a potent inhibitor of HIV-1. Methyl salvionolate A inhibits P24 antigen in HIV-1 infected MT-4 cell with an EC50 of 1.62 μg/ml. Methyl salvionolate A also inhibits HIV-1 reverse transcriptase, protease and integrase with IC50s of 50.58, 10.73 and 7.58 μg/ml, respectively[1].
• Target Antigen: HIV
• Type: Natural Products
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/methyl-salvionolate-a.html
• Solubility: 10 mM in DMSO
• Smiles: OC(C=C1/C=C/C2=C(C=CC(O)=C2O)/C=C/C(O[C@@H](C(OC)=O)CC3=CC(O)=C(C=C3)O)=O)=C(C=C1)O
• Molecular Weight: 508.47
• References & Citations: [1]Wang Q, et al. Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis. J Nat Prod. 2018 Nov 26;81(11):2531-2538.|[2]Zhang ZF, et al. Three new derivatives of anti-HIV-1 polyphenols isolated from Salvia yunnanensis. J Asian Nat Prod Res. 2008 May-Jun;10(5-6):391-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported