Ethyl salvianolate A

• Description :

  Ethyl salvianolate A (Ethyl salvionolate A) is an anti-HIV-1 compound that can be extracted from the roots of Salvia yunnanensis. Ethyl salvianolate A inhibits P24 antigen in HIV-1 infected MT-4 cell cultures (EC50: 1.44 μg/mL) . Ethyl salvianolate A inhibits HIV-1 replicative enzymes, with IC50s of 56.38 μM (Reverse transcriptase), 12.03 μM (Protease), 14.54 μM (Integrase), respectively[1].

• CAS Number :

  [1015171-68-2]

• Product Name Alternative :

  Ethyl salvionolate A

• UNSPSC :

  12352005

• Target :

  HIV; HIV Integrase; HIV Protease; Reverse Transcriptase

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research :

  Infection

• Purity :

  91.38

• Solubility :

  DMSO : 100 mg/mL

• Smiles :

  OC(C=C1/C=C/C2=C(C=CC(O)=C2O)/C=C/C(O[C@@H](C(OCC)=O)CC3=CC(O)=C(C=C3)O)=O)=C(C=C1)O

• Molecular Formula :

  C28H26O10

• Molecular Weight :

  522.50

• References & Citations :

  [1]Zhang ZF, et al. Three new derivatives of anti-HIV-1 polyphenols isolated from Salvia yunnanensis. J Asian Nat Prod Res. 2008 May-Jun;10 (5-6) :391-6.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  HIV-1