Ethyl salvianolate A

• Description:

  Ethyl salvianolate A (Ethyl salvionolate A) is an anti-HIV-1 compound that can be extracted from the roots of Salvia yunnanensis. Ethyl salvianolate A inhibits P24 antigen in HIV-1 infected MT-4 cell cultures (EC50: 1.44 μg/mL) . Ethyl salvianolate A inhibits HIV-1 replicative enzymes, with IC50s of 56.38 μM (Reverse transcriptase), 12.03 μM (Protease), 14.54 μM (Integrase), respectively[1].

• Product Name Alternative:

  Ethyl salvionolate A

• UNSPSC:

  12352005

• Target:

  HIV; HIV Integrase; HIV Protease; Reverse Transcriptase

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Purity:

  91.38

• Solubility:

  DMSO : 100 mg/mL

• Smiles:

  OC (C=C1/C=C/C2=C (C=CC (O) =C2O) /C=C/C (O[C@@H] (C (OCC) =O) CC3=CC (O) =C (C=C3) O) =O) =C (C=C1) O

• Molecular Formula:

  C28H26O10

• Molecular Weight:

  522.50

• References & Citations:

  [1]Zhang ZF, et al. Three new derivatives of anti-HIV-1 polyphenols isolated from Salvia yunnanensis. J Asian Nat Prod Res. 2008 May-Jun;10 (5-6) :391-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  HIV-1

• CAS Number:

  1015171-68-2