Recombinant Mouse Exodus-2 (CCL21A)

Recombinant Mouse Exodus-2 (CCL21A)

• Description: Exodus-2 has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. Exodus-2 selectively stimulates the chemotaxis of adult T-lymphocytes and is expressed preferentially in lymph node tissue. Exodus-2 is critical for adult T-cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T cell trafficking through nodal tissue.
• CAS Number: 9000-83-3
• Gene Name: CCL21A
• Gene Aliases: C-C motif chemokine 21a, 6Ckine, Beta-chemokine exodus-2, Small-inducible cytokine A21a, Thymus-derived chemotactic agent 4, TCA4, Scya21, Scya21a, Ccl21a
• Gene ID: 65956
• Accession Number: P84444
• Organism: Mouse
• Source: E. coli
• Concentration: <1.0 EU/μg of recombinant protein as determined by the LAL method.
• Purity: >95% as determined by SDS-PAGE
• Solubility: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
• Function: Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10-100 ng/mL.
• Molecular Weight: 12
• Shipping Conditions: Ambient Temperature
• Storage Conditions: The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
• Appearance: Lyophilized Powder
• Formulation: Recombinant mouse Exodus-2 was lyophilized from a 0.2 μm filtered PBS solution.