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Recombinant Human VEGF (121aa)

CAT: 0171-Z102117Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Z102117Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VEGF is a heavily glycosylated, homodimeric protein. The human factor occurs in several molecular variants of 121, 162, 145, 148, 165, 183, 189, 206 amino acids, arising by alternative splicing of the mRNA. The splice forms of VEGF differ in biological properties such as the receptor types, which they recognize and their interaction with heparan sulfate proteoglycans. VEGF121 and VEGF165 are soluble secreted forms of the factor. The interaction of VEGF with heparin-like molecules of the extracellular matrix is required for efficient receptor binding. Protamine sulfate and suramin are capable of replacing the receptor-bound factor. This recombinant construct represents the isoform 121 of VEGFA.
CAS Number
9000-83-3
Gene Name
VEGFA
Gene Aliases
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF-121aa, Recombinant Human Vascular Endothelial Growth Factor 121AA (VEGFA)
Gene ID
7422
Accession Number
P15693
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED50 as determined by the dose-dependent proliferation of human umbilical vein endothelial cells (HUVEC) was found to be 10 ng/mL
Molecular Weight
14.3
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from 0.2 μm filtered solution in Tris and NaCl, pH 8.0

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Alternative Products

CatalogName
MBS4159823-01Recombinant Human VEGF (121aa)
MBS554045-01Human VEGF 121AA Recombinant (CHO Cell)
RP0923U-01Rabbit VEGF-A (121aa) Recombinant Protein
MBS554178-01Human VEGF 121AA Recombinant (E coli)
500534-01VEGF (121aa), Recombinant, Human (Vascular Endothelial Growth Factor A, VEGF-A, Vascular Permeability Factor, VPF, VEGF-121aa, Vascular Endothelial Growth Factor 121aa (VEGFA) discontinued
MBS554070-01Human VEGF 121AA Recombinant (CHO Cell), Biotinylated
RP1610H-01Multi-species (Human, Monkey) VEGF-A (121aa) Recombinant Protein
500538VEGF, Recombinant, Human (Vascular Endothelial Growth Factor A, VEGF-A, Vascular Permeability Factor, VPF, 121aa) discontinued
500537VEGF, Recombinant, Human (Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, 165aa, Vascular Endothelial Growth Factor 121AA, VEGFA) discontinued
500536VEGF, Recombinant, Human (Vascular Endothelial Growth Factor A, VEGF-A, Vascular Permeability Factor, VPF, Vascular Endothelial Growth Factor 165AA, 121aa, VEGFA) discontinued

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