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Recombinant Human TWEAK (TNFSF12)

CAT: 0171-Z102275Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0171-Z102275Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TWEAK is a TNF superfamily transmembrane protein which is expressed in many different cells and tissues, such as the heart, spleen and small intestine. Two different receptors have been identified that bind TWEAK; the Death Receptor 3 (DR3) and the TWEAK Receptor (TWEAKR). While DR3 is expressed mainly in tissues that have high concentration of lymphocytes, the mitogen-inducible TWEAKR is has been shown to be expressed in fibroblasts, hepetocellular carcinomas and endothelial cells. Recombinant human TWEAK comprises the TNF homologous (secreted region) of TWEAK.
CAS Number
9000-83-3
Gene Name
TNFSF12
Gene Aliases
TWEAK, Tumor necrosis factor ligand superfamily member 12, TNFSF12, DR3LG, Apo3-Ligand
Recombinant Human TNF-Related Weak Inducer of Apoptosis (TNFSF12)
Gene ID
407977
Accession Number
O43508
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 0.1mg/ml/mL in sterile PBS containing at least 0.1% human or bovine serum albumin
Molecular Weight
17.2
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein

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