Recombinant Human MANF

CAT: 0171-Z102067Size: 200 µgDry Ice: NoHazardous: No
CAT#:0171-Z102067Size:200 µg
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Description
MANF is a neurotrophic factor found mainly in central nervous tissues where it may remain localized to the endoplasmic reticulum/Golgi apparatus, or secreted. It has been shown that MANF plays an important role in protecting cells against tunicamycin and thapsigargin -induced cell death. Without MANF, cells become increasingly vulnerable to the aforementioned drugs. Also, MANF is structurally homologous to CDNF.
CAS Number
9000-83-3
Gene Name
MANF
Gene Aliases
Arginine-rich protein, Protein ARMET, ARP
Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Gene ID
7873
Accession Number
P55145
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 200 μg/mL in PBS
Function
N.A.
Molecular Weight
18.4
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS

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