Active MANF, Human Recombinant

CAT: 0026-P1706-25Size: 25 µgDry Ice: NoHazardous: No
CAT#:0026-P1706-25Size:25 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MANF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote the survival, growth and function of dopamine-specific neurons. MANF can prevent 6-OHDA-induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson's disease. Expression of MANF has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
12 months

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