Recombinant Human Lymphotactin (XCL1)

• Description:

  XCL1, also known as lymphotactin or ATAC, is the sole member of the C subgroup of chemokines, and more importantly, is produced mainly by activated CD8 T cells (and to a lesser extent by natural killer and mast cells). The chemotactic activity of XCL1 is restricted to lymphocytes and has no effect on monocytes.

• Gene Name:

  XCL1

• Gene Aliases:

  ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1, XCL1, LTN, SCYC1

• Gene ID:

  6375

• Accession Number:

  P47992

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function:

  Activity was determined by the ability to induce chemotaxis of human T-cells at concentrations ranging between 50-100 ng/ml.

• Molecular Weight:

  10

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Recombinant Lymphotactin was lyophilzed from 0.2μm filtered PBS, pH 7.0.

• CAS Number:

  9000-83-3