Recombinant Human CCL21

CAT: 0171-Z100199Size: 1 mgDry Ice: NoHazardous: No
CAT#:0171-Z100199Size:1 mg
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Description
CCL21, which is a member of the family of CC-Chemokines, has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. CCL21 selectively stimulates the chemotaxis of adult T lymphocytes and is expressed preferentially in lymph node tissue. CCL21 is critical for adult T cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T cell trafficking through nodal tissue.
CAS Number
9000-83-3
Gene Name
CCL21
Gene Aliases
C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, SLC, Small-inducible cytokine A21, SCYA21
Recombinant Human Secondary Lymphoid-Tissue Chemokine (CCL21)
Gene ID
6366
Accession Number
O00585
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10-100 ng/mL.
Molecular Weight
12
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant CCL21 was lyophilized from a 0.2 μm filtered solution in 2.5% glycine, 0.5% sucrose, 0.01% Tween80, 5 mM Glutamic acid, pH 4.5.

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