Recombinant Human IL22

• Description:

  Originally identified as a gene induced by IL-9 in mouse T cells and mast cells, IL-22 is a member of the IL-10 family of cytokines. IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the pancreas and liver. The IL-22 receptor complex consists of two receptor subunits, IL-22R and IL-10R-beta that belong to the class II cytokine receptor family. Recombinant human IL-22 is a non-disulfide-linked homodimeric protein.

• Gene Name:

  IL22

• Gene Aliases:

  IL-22, IL-TIF, Cytokine Zcyto18, IL-10-related T cell-derived-inducible factor, ILTIF, ZCYTO18
  Recombinant Human Interleukin-22 (IL22)

• Gene ID:

  50616

• Accession Number:

  Q9GZX6

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function:

  Activity was determined by the ability to inhibit growth of human A549 cancer cells at concentrations ranging between 50-100 ng/mL.

• Molecular Weight:

  17

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Recombinant Interleukin-22 was lyophilized from 0.2 μm filtered concentrated (1.0 mg/mL) solution in 500 mM NaCl, 20 mM Tris, pH 8.0.

• CAS Number:

  9000-83-3