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Recombinant Human IL19

CAT: 0171-Z102445Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0171-Z102445Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL19 belongs to the IL-10 family of proinflammatory cytokines, which is composed of IL10, IL19, IL20, IL22, IL24, and IL26. IL19 is mainly expressed in monocytes and binds to the IL20 receptor complex which leads to the activation of the signal transducer and activator of transcription 3 (STAT3). It also performs up-regulation of IL6 and TNF-alpha and apoptosis induction, thus signifying its role in inflammatory responses.
CAS Number
9000-83-3
Gene Name
IL19
Gene Aliases
Melanoma differentiation-association protein-like protein, NG.1
Gene ID
29949
Accession Number
Q9UHD0
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute in sterile PBS at atleast 10µg/mL
Function
The ED50 is 0.5-1.5 ng/mL as determined by a cell proliferation assay with the use of transfected BaF3 mouse pro-B cells with human IL-20Rα and human IL-20Rβ
Molecular Weight
18
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 µm filtered solution in PBS

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