Recombinant Human CXCL11

• Description :

  The CXCL11 belongs to the CXC chemokine family characterized by the presence of one amino acid in between the two NH2-terminal cysteines. CXCL11 is produced by a variety of cells including leukocytes, fibroblasts, and endothelial cells upon stimulation with interferons (IFNs). Simultaneous stimulation of fibroblasts or endothelial cells with IFN-gamma and Interleukin-1b or the TLR3 ligand double-stranded RNA results in a synergistic increase of CXCL11 production. CXCL11 attracts natural killer cells and activated T-helper 1 cells. Like CXCL9 and CXCL10, CXCL11 signals through CXC chemokine receptor 3 (CXCR3).

• Gene Name :

  CXCL11

• Gene Aliases :

  CXCL11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11
  Recombinant Human IFN-Inducible T-cell Chemoattractant (CXCL11)

• Gene ID :

  6373

• Accession Number :

  O14625

• Organism :

  Human

• Source :

  E. coli

• Concentration :

  <1.0 EU/μg of recombinant protein as determined by the LAL method

• Purity :

  >95% as determined by SDS-PAGE

• Solubility :

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function :

  Determined by its ability to chemoattract human T cells using a concentration range of 2.0-10.0 ng/mL

• Molecular Weight :

  8

• Shipping Conditions :

  Ambient Temperature

• Storage Conditions :

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance :

  Lyophilized Powder

• Formulation :

  Lyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl pH 7.5

• CAS Number :

  9000-83-3