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Recombinant Human 4-BBL (TNFSF9)

CAT: 0171-Z102255Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0171-Z102255Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Human 4-BBL or TNFSF9 is a member of the TNF superfamily. It is a type 2 transmembrane protein expressed on activated T-cells. It is a bidirectional signal transducer which acts as a costimulatory receptor molecule on T lymphocytes. Its functions primarily stimulate the immune response by promoting the release of cytokines such as IL-2 and IFN-gamma. TNFSF9 works with TNFRSF9 for the generation of cytotoxic T cells, proliferation of T-cells as well as antigen presentation. It also reactivates T lymphocytes which have become anergic. It is also expressed on activated NK cells, B-cells, macrophages, dendritic cells and some brain cells. Recombinant Human 4-BBL is a 19.6 kDa protein.
CAS Number
9000-83-3
Gene Name
TNFSF9
Gene Aliases
TNFSF9, CD137L, 4BBL
Gene ID
8744
Accession Number
P41273
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
coming soon
Molecular Weight
19.6
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4

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