Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) (MRP1/1343), CF405S conjugate

Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) (MRP1/1343), CF405S conjugate

• Description: The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
• Synonyms: ABC29; ABCC1; ATP binding cassette sub family C (CFTR/MRP) member 1; ATP-binding cassette sub-family C member 1; GSX; Leukotriene C(4) transporter; LTC4 transporter; Multidrug resistance-associated protein 1 (MRP1)
• CAS Number: 9007-83-4
• UNSPSC: 41116161
• UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
• Gene Name: ABCC1
• Gene ID: 4363
• NCBI Gene ID: 391464
• UniProt: P33527
• Cellular Locus: Plasma membrane
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Recombinant human full-length ABCC1
• Target Antigen: ABCC1 | MRP1
• Clonality: Monoclonal
• Isotype: IgG1
• Clone: MRP1/1343
• Conjugation: CF405S
• Disease: Tumor
• Source: Animal
• Field of Research: Cancer, Transporters
• Positive Control: A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.
• Concentration: 0.1 mg/mL
• Buffer: PBS, 0.1% BSA, 0.05% azide
• Molecular Weight: 190 kDa
• Additionnal Information: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
• Shipping Conditions: Room temperature
• Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
• Shelf Life: 2 years