PI3K-IN-30

PI3K-IN-30

• CAS Number: 2281803-22-1
• UNSPSC Description: PI3K-IN-30 (compound 6d) is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively[1].
• Target Antigen: PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3k-in-30.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: COCCN(CCO)C1=NC(N2C3=CC=CC=C3N=C2C(F)F)=NC(N4CCOCC4)=N1
• Molecular Weight: 449.45
• References & Citations: [1]Van Dort ME, et al. Structural effects of morpholine replacement in ZSTK474 on Class I PI3K isoform inhibition: Development of novel MEK/PI3K bifunctional inhibitors. Eur J Med Chem. 2022;229:113996.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported