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Moxonidine (Standard)

CAT: 0804-HY-B0374R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0374R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Moxonidine (Standard) is the analytical standard of Moxonidine. This product is intended for research and analytical applications. Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I1-R) agonist. Moxonidine activates imidazoline I1 receptors and α2 adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis[1][2][3][4][5][6][7].
CAS Number
75438-57-2
Product Name Alternative
BDF5895 (Standard)
UNSPSC
12352005
Target
Adrenergic Receptor; Imidazoline Receptor; LDLR; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/moxonidine-standard.html
Smiles
CC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1
Molecular Formula
C9H12ClN5O
Molecular Weight
241.68
References & Citations
[1]Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303 (3) : p. 1163-70.|[2]Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132 (4) : p. 991-1007.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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