DAPK1 (Phospho-Ser308) rabbit pAb

• Background:

  Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

• Description:

  Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

• Synonyms:

  Death-associated protein kinase 1 (DAP kinase 1;EC 2.7.11.1)

• Gene ID:

  1612

• UniProt:

  P53355

• Cellular Locus:

  [Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with MAP1B in the microtubules and cortical actin fibers.; [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human DAPK1 (Phospho-Ser308)

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC, IF, WB

• Validated Applications:

  IHC, IF, WB

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  IHC-p 1:50-200, WB 1:500-2000

• Molecular Weight:

  160kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  160 kD

• Subcellular Location:

  [Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with MAP1B in the microtubules and cortical actin fibers.; [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton.

• Other Product Names:

  Death-associated protein kinase 1 (DAP kinase 1; EC 2.7.11.1)

• Gene ID (Human):

  1612

• SwissProt (Human):

  P53355