Anti-TGFalpha(TGFA/1119), CF647 conjugate
CAT:
37-BNC471119-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-TGFalpha(TGFA/1119), CF647 conjugate
- Description: This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF-beta (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: EGF-like TGF; ETGF; TFGA; TGF Type 1; TGFA; Wa1; Waved 1
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: TGFA
- Gene ID: 7039
- NCBI Gene ID: 170009
- UniProt: P01135
- Cellular Locus: Secreted (extracellular)
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant human full-length TGF alpha protein
- Target Antigen: TGF-Alpha
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: TGFA/1119
- Conjugation: CF647
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Field of Research: Signal transduction
- Positive Control: Jurkat or Ramos cells. Testicular Carcinoma
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 6 kDa
- Additionnal Information: Immunohistology formalin-paraffin 2-4 ug/mL|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Immunofluorescence 1-2 ug/mL|Optimal dilution for a specific application should be determined by user
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years