Entecavir (monohydrate) (Standard)

• UNSPSC Description:

  Entecavir (monohydrate) (Standard) is the analytical standard of Entecavir (monohydrate). This product is intended for research and analytical applications. Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.

• Target Antigen:

  HBV

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/entecavir-monohydrate-standard.html

• Smiles:

  NC(N1)=NC(C2=C1N([C@@H](C[C@H](O)[C@H]3CO)C3=C)C=N2)=O.O

• Molecular Weight:

  295.29

• References & Citations:

  [1]Innaimo SF, et al. Identification of?BMS-200475?as a potent and selective inhibitor of hepatitis B virus. Antimicrob Agents Chemother. 1997 Jul;41(7):1444-8.|[2]Rivkin A, et al. A review of entecavir in the treatment of chronic hepatitis B infection. Curr Med Res Opin.?2005 Nov;21(11):1845-56.|[3]Genovesi EV, et al. Efficacy of the carbocyclic 2'-deoxyguanosine nucleoside?BMS-200475?in the woodchuck model of hepatitis B virus infection. Antimicrob Agents Chemother.?1998 Dec;42(12):3209-17.

• Shipping Conditions:

  Room temperature

• CAS Number:

  209216-23-9