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Cefaclor (monohydrate) (Standard)

CAT: 0804-HY-B0198ARSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0198ARSize:1 Each
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Description
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate) . This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3) . Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections[1][2][3][4].
CAS Number
70356-03-5
UNSPSC
12352005
Target
5-HT Receptor; Antibiotic; Bacterial; Penicillin-binding protein (PBP) ; Reference Standards
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cefaclor-monohydrate-standard.html
Smiles
O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O.[H]O[H]
Molecular Formula
C15H16ClN3O5S
Molecular Weight
385.82
References & Citations
[1]1 : Joo MK, et al. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Sci Rep. 2023 Sep 19;13 (1) :15529. |[2]Li M, et al. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab Dispos. 2006 Apr;34 (4) :547-55. |[3]Yoo HS, et al. Immunologic evaluation of immediate hypersensitivity to cefaclor. Yonsei Med J. 2014 Nov;55 (6) :1473-83. |[4]Neu HC, et al. Cefaclor: in vitro spectrum of activity and beta-lactamase stability. Antimicrob Agents Chemother. 1978 Apr;13 (4) :584-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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