Cefaclor (monohydrate) (Standard)

• Description :

  Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate) . This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3) . Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections[1][2][3][4].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; Antibiotic; Bacterial; Penicillin-binding protein (PBP) ; Reference Standards

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; GPCR/G Protein; Neuronal Signaling; Others

• Field of Research :

  Infection; Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cefaclor-monohydrate-standard.html

• Smiles :

  O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O.[H]O[H]

• Molecular Formula :

  C15H16ClN3O5S

• Molecular Weight :

  385.82

• References & Citations :

  [1]1 : Joo MK, et al. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Sci Rep. 2023 Sep 19;13 (1) :15529. |[2]Li M, et al. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab Dispos. 2006 Apr;34 (4) :547-55. |[3]Yoo HS, et al. Immunologic evaluation of immediate hypersensitivity to cefaclor. Yonsei Med J. 2014 Nov;55 (6) :1473-83. |[4]Neu HC, et al. Cefaclor: in vitro spectrum of activity and beta-lactamase stability. Antimicrob Agents Chemother. 1978 Apr;13 (4) :584-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [70356-03-5]