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ADS031

CAT: 0804-HY-161333Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-161333Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ADS031, a histamine H3R antagonist, displays 12.5 nM affinity at the hH3R and the highest inhibitory activity against AChE (IC50 = 1.537 μM) [1].
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ads031.html
Solubility
10 mM in DMSO
Smiles
CN(CCC)CC1=CC2=CC=C(C=C2C=C1)COC(CC3)CCN3CC4=CC=CC=C4
Molecular Formula
C28H36N2O
Molecular Weight
416.60
References & Citations
[1]Beata Michalska, et al. 4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H3 Receptors and Cholinesterases. ACS Chem Neurosci. 2024 Mar 5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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