Val-Ala-PAB

• Description:

  Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis[1].

• UNSPSC:

  12352200

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/val-ala-pab.html

• Purity:

  99.88

• Solubility:

  DMSO : 116.67 mg/mL (ultrasonic)

• Smiles:

  CC(C)[C@H](N)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O

• Molecular Formula:

  C15H23N3O3

• Molecular Weight:

  293.37

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Cox N, et al. Integrin-Targeting Knottin Peptide-Drug Conjugates Are Potent Inhibitors of Tumor Cell Proliferation. Angew Chem Int Ed Engl. 2016 Aug 16;55 (34) :9894-7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [1343476-44-7]