ANK peptide

• Description:

  ANK peptide is a novel peptide designed based on the conserved residues of single ankyrin motif. ANK peptide is a synuclein-γ (SNCG) inhibitor that binds to SNCG and competes with SNCG-BubR1 interaction to enhance the sensitivity of breast cancer cells to antimicrotubule drugs such as nocodazole and paclitaxel. ANK peptide can be used in the study of cancer[1].

• UNSPSC:

  12352209

• Target:

  Amino Acid Derivatives

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Smiles:

  NCCCC[C@H](N)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CS)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@H](C(NCC(O)=O)=O)CC1=CN=CN1)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C152H244N52O46S2

• Molecular Weight:

  3600.01

• References & Citations:

  [1]Singh VK, et al. Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs. Cancer Res. 2007 Jan 15;67 (2) :626-33.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [929207-58-9]