PDE12-IN-3

PDE12-IN-3

• CAS Number: 1803357-22-3
• UNSPSC Description: PDE12-IN-3 is a phosphodiesterase 12 (PDE12) inhibitor with a pXC50 of 7.68. Antiviral activity[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pde12-in-3.html
• Purity: 98.02
• Solubility: DMSO : 80 mg/mL (ultrasonic)
• Smiles: N#CC1=CC2=C(C=C1)C(C3=NC4=CC=C(C(N5C(CO)C(C6=CC=CC=C6)OCC5)=O)C=C4N3C)=CN2
• Molecular Weight: 491.54
• References & Citations: [1]Wood ER, et al. The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. J Biol Chem. 2015 Aug 7;290(32):19681-96.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported