Anti-Melanoma Marker(KBA.62)

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Alternative Products

Cat	Name
MBS370216-01	Melanoma KBA.62
MBS370216-02	Melanoma KBA.62
MBS370216-03	Melanoma KBA.62
MBS370216-04	Melanoma KBA.62
MBS370216-05	Melanoma KBA.62
MBS191522-01	KBA.62 (Melanoma Associated Antigen)
MBS344019-01	KBA.62 (Melanoma Associated Antigen)
MBS191522-02	KBA.62 (Melanoma Associated Antigen)
MBS344019-02	KBA.62 (Melanoma Associated Antigen)
MBS344019-03	KBA.62 (Melanoma Associated Antigen)

Anti-Melanoma Marker(KBA.62)

CAT:

37-BNUB0895-500

Size:

500 µL

Price:

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Anti-Melanoma Marker(KBA.62)

Description: KBA.62 is a novel anti-melanoma antibody. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, it reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. KBA.62 antibody is useful in identifying malignant melanomas. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, sarcomas, spindle cell carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immuno-reacts with antibody to S-100 protein and with KBA.62 antibody is, with rare exception, a melanoma. Anti-KBA.62 is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases and in the context of micro-metastasis in sentinel lymph node.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Synonyms: Human Melanoma Associated Antigen; KBA.62
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: Not Known
NCBI Gene ID: Not Known
UniProt: Not Known
Cellular Locus: Cytoplasmic|Plasma membrane
Host: Mouse
Species Reactivity: Human
Immunogen: Human KAL cells derived from lymph node metastasis of malignant melanoma
Target Antigen: Melanoma Marker
Clonality: Monoclonal
Isotype: IgG1 κ
Clone: KBA.62
Conjugation: Purified, with BSA
Disease: Tumor
Source: Animal
Applications: IHC, FFPE (verified)
Validated Applications: IHC, FFPE
Field of Research: Cancer
Positive Control: SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: Multiple (140, 135 and 128 kDa and two weak bands of 88 and 73 kDa)
Additionnal Information: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Immunohistology (formalin)|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Optimal dilution for a specific application should be determined by user
Shipping Conditions: Room temperature
Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: 2 years

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Cat	Name
BNUB0895-100	Anti-Melanoma Marker(KBA.62)
BNUB0895-500	Anti-Melanoma Marker(KBA.62)
BNUM0895-50	Anti-Melanoma Marker(KBA.62)
BNC740895-100	Anti-Melanoma Marker(KBA.62), CF740 conjugate
BNC740895-500	Anti-Melanoma Marker(KBA.62), CF740 conjugate
BNC040895-500	Anti-Melanoma Marker(KBA.62), CF405S conjugate
BNC470895-500	Anti-Melanoma Marker(KBA.62), CF647 conjugate
BNC680895-100	Anti-Melanoma Marker(KBA.62), CF568 conjugate
BNC880895-500	Anti-Melanoma Marker(KBA.62), CF488A conjugate
BNC040895-100	Anti-Melanoma Marker(KBA.62), CF405S conjugate