Products for Research Use Only
RegisterLogin

Flufenamic acid (Standard)

CAT: 0804-HY-B1221R-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1221R-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Flufenamic acid (Standard) is the analytical standard of Flufenamic acid. This product is intended for research and analytical applications. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
CAS Number
530-78-9
UNSPSC
12352005
Target
AMPK; Calcium Channel; Chloride Channel; COX; Parasite; Potassium Channel; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Epigenetics; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling; Others; PI3K/Akt/mTOR
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/flufenamic-acid-standard.html
Smiles
O=C(O)C1=CC=CC=C1NC2=CC=CC(C(F)(F)F)=C2
Molecular Formula
C14H10F3NO2
Molecular Weight
281.23
References & Citations
[1]Guinamard R, et al. Flufenamic acid as an ion channel modulator. Pharmacol Ther. 2013 May;138 (2) :272-84.|[2]Pongkorpsakol P, et al. Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-κB inhibition and AMPK activation. Eur J Pharmacol. 2017 Mar 5;798:94-104.|[3]Pongkorpsakol P, et al. Cellular mechanisms underlying the inhibitory effect of flufenamic acid on chloride secretion in human intestinal epithelial cells. J Pharmacol Sci. 2017 Jun;134 (2) :93-100.|[4]Pobbati AV, et al. Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy. Structure. 2015;23 (11) :2076-2086.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-B1221-01Flufenamic acid
HY-B1221S-01Flufenamic acid-d4
HY-B1221S1-01Flufenamic acid-13C6
HY-N9457RNorcholic acid (Standard)
HY-N2998RGanoderenic acid A (Standard)
HY-N2318RPodocarpic acid (Standard)
HY-W338852R-01Gentisuric acid (Standard)
HY-W127758RAlginic acid (Standard)
HY-W115529RGeranic acid (Standard)
HY-W037875Rα-Acetamidocinnamic acid (Standard)

Alternative Products

CatalogName
T0858-01Flufenamic acid

Popular Products