WM-3835

WM-3835

• CAS Number: 2229025-70-9
• UNSPSC Description: WM-3835 is a potent and high-specific HBO1 (KAT7 or MYST2) inhibitor and binds directly to the acetyl-CoA binding site of HBO1. WM-3835 activates apoptosis while inhibits osteosarcoma (OS) cell proliferation, migration and invasion. WM-3835 has antitumor activity and potently inhibits pOS-1 xenograft growth in mice[1].
• Target Antigen: Apoptosis; Histone Acetyltransferase
• Type: Reference compound
• Related Pathways: Apoptosis;Epigenetics
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/wm-3835.html
• Smiles: O=C(C1=CC(C2=CC=CC=C2)=CC(C)=C1F)NNS(=O)(C3=CC=CC(O)=C3)=O
• Molecular Weight: 400.42
• References & Citations: [1]Yan-Yang Gao, et al. The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma. Theranostics. 2021 Mar 4;11(10):4599-4615.
• Shipping Conditions: Room Temperature