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CDC14A/B-IN-1

CAT: 0804-HY-161673Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161673Size:1 Each
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Description
CDC14A/B-IN-1 (Compound 15) is an orally available inhibitor of CDC14A/B phosphatases with Ki values of 57.4 nM (CDC14A) and 90.0 nM (CDC14B), respectively[1].
CAS Number
3048655-03-1
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cdc14a-b-in-1.html
Smiles
FC(F)(P(O)(O)=O)C1=C2C(OC3=C2C=CC=C3)=C(C=C1)C(C4=CC=CC=C4)=C
Molecular Formula
C21H15F2O4P
Molecular Weight
400.31
References & Citations
[1]Dong J, et al. Development of Novel Phosphonodifluoromethyl-Containing Phosphotyrosine Mimetics and a First-In-Class, Potent, Selective, and Bioavailable Inhibitor of Human CDC14 Phosphatases. J Med Chem. 2024 Jun 13;67 (11) :8817-8835.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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