Human FASR/TNFRSF6 (Recombinant)

• Description:

  Human FASR/TNFRSF6_x000D_ Catalog number: B2010358_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human FASR/TNFRSF6 expressed in HEK 293. This protein acts as a protein that belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that can trigger apoptosis._x000D_ Storage: -20C_x000D_ Keywords: rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; FAS1; Apo-1_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Mehrbod P, Ande SR, Alizadeh J, Rahimizadeh S, Shariati A, Malek H, Hashemi_x000D_ M, Glover KKM, Sher AA, Coombs KM, Ghavami S. The roles of apoptosis, autophagy_x000D_ and unfolded protein response in arbovirus, influenza virus, and HIV infections._x000D_ Virulence. 2019 Dec;10(1):376-413._x000D_ _x000D_ 2: Mondino S, Vázquez CL, Cabruja M, Sala C, Cazenave-Gassiot A, Blanco FC, Wenk_x000D_ MR, Bigi F, Cole ST, Gramajo H, Gago G. FasR Regulates Fatty Acid Biosynthesis_x000D_ and Is Essential for Virulence of Mycobacterium tuberculosis. Front_x000D_ Microbiol. 2020 Oct 27;11:586285._x000D_ _x000D_ 3: Klatt C, Krüger I, Zey S, Krott KJ, Spelleken M, Gowert NS, Oberhuber A,_x000D_ Pfaff L, Lückstädt W, Jurk K, Schaller M, Al-Hasani H, Schrader J, Massberg S,_x000D_ Stark K, Schelzig H, Kelm M, Elvers M. Platelet-RBC interaction mediated by_x000D_ FasL/FasR induces procoagulant activity important for thrombosis. J Clin Invest._x000D_ 2018 Aug 31;128(9):3906-3925._x000D_ _x000D_ 4: Sathaiah M, Thirunavukkarasu P, O'Malley ME, Kavanagh MA, Ravindranathan R,_x000D_ Austin F, Guo ZS, Bartlett DL. Oncolytic poxvirus armed with Fas ligand leads to_x000D_ induction of cellular Fas receptor and selective viral replication in FasR-_x000D_ negative cancer. Cancer Gene Ther. 2012 Mar;19(3):192-201._x000D_ _x000D_ 5: Wasiluk A, Ratomski K, Wnuczko K, Zak J, Szczepański M, Wysocka J, Jasińska_x000D_ EA. Expression of FasR, Fas-L and Bcl-2 in CD4+ and CD8+ subpopulations of T_x000D_ lymphocytes in the cord blood of healthy full-term newborns, is gender of_x000D_ influence? Adv Med Sci. 2009;54(1):99-103._x000D_ _x000D_ 6: Chen J, Zhang H, Su F, Min J, Zhang J, Song E. Cytokine associated_x000D_ sensitivity of colon carcinoma cells to FasR-mediated cytotoxicity of CTL. Asian_x000D_ J Surg. 2002 Jan;25(1):89-97._x000D_ 7: Shadrin N, Shapira MG, Khalfin B, Uppalapati L, Parola AH, Nathan I. Serine_x000D_ protease inhibitors interact with IFN-γ through up-regulation of FasR; a novel_x000D_ therapeutic strategy against cancer. Exp Cell Res. 2015 Jan 15;330(2):233-239._x000D_ 8: Keyser BM, Andres DK, Nealley E, Holmes WW, Benton B, Paradiso D, Appell A,_x000D_ Carpin C, Anderson DR, Smith WJ, Ray R. Postexposure application of Fas receptor_x000D_ small-interfering RNA to suppress sulfur mustard-induced apoptosis in human_x000D_ airway epithelial cells: implication for a therapeutic approach. J Pharmacol Exp_x000D_ Ther. 2013 Jan;344(1):308-16. _x000D_ _x000D_ Products Related to Human FASR/TNFRSF6 : Proteins

• Short Description:

  Catalog Number: B2010358 (10 ug)_x000D_ Human FASR/TNFRSF6 is a high quality research product used as highly pure Human FASR/TNFRSF6 expressed in HEK 293. This protein acts as a protein that belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that can trigger apoptosis. Custom bulk orders of this product are available upon request.

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3