1"-α-Azido-RDPr

CAT: 0804-HY-163785Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-163785Size:1 Each

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Description

1"-α-Azido-RDPr (Compound 11) is an analog of adenosine diphosphate ribose, and exhibits inhibitory efficacy against the SARS-CoV-2 nonstructural protein macodomain SARS-CoV-2 NSP3 Mac1 with an IC50 of 30 nM[1].

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/1-α-azido-rdpr.html

Smiles

O[C@@H]1[C@H](O)[C@@H](OP(OP(O)(OC[C@H]2O[C@H](N=[N+]=[N-])[C@H](O)[C@@H]2O)=O)(O)=O)O[C@@]1(C#N)C3=CC=C4N3N=CN=C4N.N.N

Molecular Formula

C16H26N10O13P2

Molecular Weight

628.38

References & Citations

[1]Rijpkema KJ, et al., Synthesis of Structural ADP-Ribose Analogues as Inhibitors for SARS-CoV-2 Macrodomain 1. Org Lett. 2024 Jul 12;26 (27) :5700-5704.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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