S9-A13

• Description:

  S9-A13 is a potent and selective inhibitor SLC26A9, with the IC50 of 90.9 nM, without inhibiting other members of the SLC26 family such as SLC26A3, SLC26A4, and SLC26A6. S9-A13 can inhibits SLC26A9 Cl- currents in cells that lack expression of CFTR[1].

• UNSPSC:

  12352005

• Target:

  Chloride Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/s9-a13.html

• Purity:

  99.68

• Smiles:

  O=C1NC2=C(C(C1)C(C3=CC=C(C)S3)=O)C(C)=NN2C4=CC=C(C)C(Cl)=C4

• Molecular Formula:

  C20H18ClN3O2S

• Molecular Weight:

  399.89

• References & Citations:

  [1]Sungwoo Jo, et al. The SLC26A9 inhibitor S9-A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion. FASEB J. 2022 Nov;36 (11) :e22534.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1223771-84-3]