Leucomycin A13

• Description :

  Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 μg/mL, respectively. It binds to ribosomes with an IC50 value of 1.2 μM in a radioligand binding assay.

• Product Name Alternative :

  Kitasamycin A13

• UNSPSC :

  12352005

• Target :

  Antibiotic

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/leucomycin-a13.html

• Smiles :

  O=CC[C@@H](C[C@H]([C@H](/C=C/C=C/C[C@H]1C)O)C)[C@@H]([C@H]([C@@H](CC(O1)=O)O)OC)O[C@H](O[C@@H]2C)[C@@H]([C@H]([C@@H]2O[C@H](O[C@H]3C)C[C@@](O)([C@H]3OC(CCCCC)=O)C)N(C)C)O

• Molecular Formula :

  C41H69NO14

• Molecular Weight :

  799.98

• References & Citations :

  [1]Tanaka, et al. Quantitative structure-activity relationships of O-acyl derivatives of leucomycin for antimicrobial and ribosome-binding activities. Chem. Pharm. Bull. (Tokyo) 33 (7), 2803-2808 (1985) .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [78897-52-6]