Clovibactin (TFA)

Clovibactin (TFA)

• UNSPSC Description: Clovibactin TFA is the TFA salt form of Clovibactin (HY-P10027). Clovibactin TFA is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors[1].
• Target Antigen: Antibiotic; Bacterial
• Type: Peptides
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/clovibactin-tfa.html
• Purity: 97.10
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: N[C@@H](CC1=CC=CC=C1)C(N[C@H](CC(C)C)C(N[C@H](CCCCN)C(N[C@@H](CO)C(N[C@@H]2[C@@H](OC([C@@H](NC([C@@H](NC([C@@H](NC2=O)C)=O)CC(C)C)=O)CC(C)C)=O)C(N)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
• Molecular Weight: 903.08 (free base)
• References & Citations: [1]Shukla R, et al., A new antibiotic from an uncultured bacterium binds to an immutable target. bioRxiv [Preprint]. 2023 May 15:2023.05.15.540765.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported