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GFAP (GA-5), 0.2mg/mL

CAT: 0037-BNUB0167-500Size: 1x 500 µLDry Ice: NoHazardous: No
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CAT#:0037-BNUB0167-500Size:1x 500 µL
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Description
This MAb recognizes a protein of ~50 kDa which is identified as Glial Fibrillary Acidic Protein (GFAP) . It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
Astrocyte or Intermediate Filament Protein, Glial Fibrillary Acidic Protein (GFAP)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GFAP
Gene ID
2670
NCBI Gene ID
514227
UniProt
P14136
Swiss Prot
P14136
Host
Mouse
Species Reactivity
Chicken, Cow, Human, Mouse, Pig, Rabbit, Rat
Reactivity
GFAP
Immunogen
GFAP isolated from pig spinal cord
Target Antigen
GFAP
Clonality
Monoclonal
Clone
GA-5
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Neuroscience
Positive Control
Brain or Astrocytoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
~50 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

UniProtKB · P14136

Glial fibrillary acidic protein

GFAP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P14136
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GFAP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GFAP
EC number
—
Processing
—
Secondary accessions
A7REI1, B2RD44, D3DX59, E9PAX3, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

CitrullinationMethylationPhosphoprotein

Domain

Coiled coil

Cellular component

CytoplasmIntermediate filament

Disease

Disease variantLeukodystrophy
Product Datasheet
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sc-58766GFAP (GA-5)
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sc-58766 FITCGFAP (GA-5) FITC
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