Products for Research Use Only
RegisterLogin

Eleutheroside E (Standard)

CAT: 0804-HY-N0272R-02Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0272R-02Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Eleutheroside E (Standard) is the analytical standard of Eleutheroside E. This product is intended for research and analytical applications. Eleutheroside E is an important component of Eleutheroside and has antioxidant, anti-fatigue, anti-inflammatory, antibacterial, immunomodulatory and cardioprotective effects. Eleutheroside E may inhibit the MAPK signaling pathway, thereby inhibiting H/R-induced NF-κB activation and oxidative stress, reducing metabolic reprogramming, and protecting myocardium from ischemia-reperfusion (I/R) injury. Eleutheroside E also counteracts the effects of high altitude hypobaric hypoxia (HAHI) by inhibiting inflammation and pyroptosis[1][2][3][4][5].
CAS Number
39432-56-9
UNSPSC
12352005
Target
Others; Reference Standards
Type
Reference Standards
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/eleutheroside-e-standard.html
Smiles
COC(C=C1[C@H]2[C@@](CO[C@@H]3C4=CC(OC)=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]5O)O)O[C@@H]5CO)C(OC)=C4)([H])[C@]3([H])CO2)=C(C(OC)=C1)O[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO
Molecular Formula
C34H46O18
Molecular Weight
742.72
References & Citations
[1]Chunyan He, et al. Eleutheroside E Ameliorates Arthritis Severity in Collagen-Induced Arthritis Mice Model by Suppressing Inflammatory Cytokine Release. Inflammation, Vol. 37, No. 5, October 2014 (# 2014) |[2]Jiyun Ahn, et al. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice. Evid Based Complement Alternat Med. 2013; 2013: 934183.|[3]Wang S, et al. Eleutheroside E decreases oxidative stress and NF-κB activation and reprograms the metabolic response against hypoxia-reoxygenation injury in H9c2 cells. Int Immunopharmacol. 2020 Jul;84:106513.|[4]Ma B, et al. Simultaneous determination of Eleutheroside B and Eleutheroside E in rat plasma by high performance liquid chromatography-electrospray ionization mass spectrometry and its application in a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Feb 15;917-918:84-92.|[5]Jia N, et al. Eleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr.etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3 inflammasome-mediated pyroptosis via NLRP3/caspase-1 pathway. Int Immunopharmacol. 2023 Aug;121:110423.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Eleutheroside E

Eleutheroside E is a glycoside and a lignan.

CAS Number39432-56-9
PubChem CID71312557
IUPAC Name(2S,3R,4S,5S,6R)-2-[4-[(3S,3aR,6R,6aS)-6-[3,5-dimethoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular FormulaC34H46O18
Molecular Weight742.7
XLogP-1.4
Topological Polar Surface Area254
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count18
Rotatable Bond Count12
Heavy Atom Count52
Formal Charge0
Complexity1010
SMILES
COC1=CC(=CC(=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)OC)[C@H]3[C@@H]4CO[C@@H]([C@H]4CO3)C5=CC(=C(C(=C5)OC)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)OC
InChI
InChI=1S/C34H46O18/c1-43-17-5-13(6-18(44-2)31(17)51-33-27(41)25(39)23(37)21(9-35)49-33)29-15-11-48-30(16(15)12-47-29)14-7-19(45-3)32(20(8-14)46-4)52-34-28(42)26(40)24(38)22(10-36)50-34/h5-8,15-16,21-30,33-42H,9-12H2,1-4H3/t15-,16+,21-,22-,23-,24-,25+,26+,27-,28-,29+,30-,33+,34+/m1/s1
InChIKey
FFDULTAFAQRACT-JSGUJALWSA-N
Chemical Structure
2D Structure
2D structure of Eleutheroside E
CAS: 39432-56-9
CID: 71312557
Formula: C34H46O18
MW: 742.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight742.7
XLogP3-1.4
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count18
Rotatable Bond Count12
Exact Mass742.26841461
Monoisotopic Mass742.26841461
Topological Polar Surface Area254 Ų
Heavy Atom Count52
Formal Charge0
Complexity1010
Isotope Atom Count0
Defined Atom Stereocenter Count14
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N0272-01Eleutheroside E
HY-N3802-01Eleutheroside C
HY-135646-01Eleutheroside B1
HY-N4147-01Eleutheroside D
HY-Y0248R-01(E, E) -Farnesol (Standard)
HY-N0007R-01(E, E) -Bisdemethoxycurcumin (Standard)
HY-N6066RPraeruptorin E (Standard)
HY-15551R-01E-4031 (Standard)
HY-N6772RCytochalasin E (Standard)
HY-N1966R(E) -Osmundacetone (Standard)

Alternative Products

CatalogName
300212Eleutheroside A
AB2050Eleutheroside B1
AB0872Eleutheroside E
371391Eleutheroside A discontinued
SM1075-5mgEleutheroside B
T13676-01Eleutheroside C
GTR19188399-01Eleutheroside D

Popular Products