(E, E) -Bisdemethoxycurcumin (Standard)

CAT: 0804-HY-N0007R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0007R-01Size:5 mg
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Description
(E, E) -Bisdemethoxycurcumin (Standard) is the analytical standard of (E, E) -Bisdemethoxycurcumin. This product is intended for research and analytical applications. (E, E) -Bisdemethoxycurcumin ((E, E) -Curcumin III) is a curcumin derivative with anti-inflammatory and anticancer activities[1][2][3][4][5][6].
CAS Number
[33171-05-0]
Product Name Alternative
(E, E) -Curcumin III (Standard) ; (E, E) -Didemethoxycurcumin (Standard)
UNSPSC
12352005
Target
Apoptosis; Autophagy; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Autophagy; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-e-bisdemethoxycurcumin-standard.html
Smiles
O=C(CC(/C=C/C1=CC=C(O)C=C1)=O)/C=C/C2=CC=C(O)C=C2
Molecular Formula
C19H16O4
Molecular Weight
308.33
References & Citations
[1]Lee PJ, et al. Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2. Molecules. 2015 Jan 14;20 (1) :1277-92.|[2]Chen J, et al. Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells. Food Funct. 2014 Dec 24.|[3]Luo C, et al. Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction. Oncol Lett. 2015 Jan;9 (1) :270-274.|[4]Li YB, et al. Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells. Evid Based Complement Alternat Med. 2013;2013:851714.|[5]Yodkeeree S, et al. Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA. J Nutr Biochem. 2009 Feb;20 (2) :87-95.|[6]Lai CS, et al. Bisdemethoxycurcumin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Obesity in High-Fat Diet-Fed C57BL/6 Mice. J Agric Food Chem. 2016 Feb 3;64 (4) :821-30.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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