Pipemidic acid

CAT: 0804-HY-B1210-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1210-01Size:50 mg
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Description
Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections[1][2].
CAS Number
[51940-44-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Pipemidic-acid.html
Purity
98.0
Solubility
1M NaOH : 100 mg/mL (ultrasonic; adjust pH to 12 with NaOH) |DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(CC)C2=NC(N3CCNCC3)=NC=C2C1=O)O
Molecular Formula
C14H17N5O3
Molecular Weight
303.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Iacovino R, et al. β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. Int J Mol Sci. 2013 Jun 25;14 (7) :13022-41.|[2]Aoyama H, et, al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32 (1) :104-9. |[3]Shimizu M, et, al. Pipemidic acid: absorption, distribution, and excretion. Antimicrob Agents Chemother. 1975 Apr;7 (4) :441-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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