DMT1 blocker 1
CAT:
804-HY-126301-06
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DMT1 blocker 1
- CAS Number: 1354790-56-9
- UNSPSC Description: DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo[1].
- Target Antigen: Ferroportin
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/dmt1-blocker-1.html
- Purity: 99.79
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: OC1=C(C(NC2=CC=CC=C2)=O)C(C)=NN1C3=NC=CC=C3
- Molecular Weight: 294.31
- References & Citations: [1]Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported