(R,R)-CPI-1612

(R,R)-CPI-1612

• CAS Number: 2374972-35-5
• UNSPSC Description: (R,R)-CPI-1612 is the isomer of CPI-1612 (HY-136285), and can be used as an experimental control. CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/r-r-cpi-1612.html
• Smiles: CN(N=C1)C=C1C(C=N2)=CC=C2NC([C@@H](C3=CC=CC=C3)NC[C@@H](C4=CC=C(C=C4)C#N)C)=O
• Molecular Weight: 450.53
• References & Citations: [1]Jonathan E Wilson, et al. Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor. ACS Med Chem Lett. 2020 Apr 23;11(6):1324-1329.
• Shipping Conditions: Room Temperature