L82-G17
CAT:
804-HY-148161-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
L82-G17
- CAS Number: 92285-87-5
- UNSPSC Description: L82-G17 is an uncompetitive DNA ligase I (Lig I)-selective inhibitor. L82-G17 inhibits the third step of the ligation reaction, phosphodiester bond formation. L82-G17can be used as a probe of the catalytic activity[1].
- Target Antigen: DNA/RNA Synthesis
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/l82-g17.html
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C1NN=CC(N/N=C/C2=CC(O)=CC=C2)=C1Cl
- Molecular Weight: 264.67
- References & Citations: [1]Timothy R L Howes, et al. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. DNA Repair (Amst). 2017 Dec;60:29-39.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported