Amino-PEG3-2G degrader-1 (hydrochloride)
CAT:
804-HY-158985A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Amino-PEG3-2G degrader-1 (hydrochloride)
- UNSPSC Description: Amino-PEG3-2G degrader-1 hydrochloride is the hydrochloride salt form of Amino-PEG3-2G degrader-1 (HY-158985). Amino-PEG3-2G degrader-1 hydrochloride is a conjugate of a PEG Linker and a pyrazole-linked FBnG tag for ubiquitin-proteasome system (UPS) induction. Amino-PEG3-2G degrader-1 hydrochloride can be used to synthesize autophagy-targeting chimeras (AUTACs)[1].
- Target Antigen: AUTACs; Autophagy
- Type: Reference compound
- Related Pathways: Autophagy;PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/amino-peg3-2g-degrader-1-hydrochloride.html
- Purity: 99.04
- Smiles: O=C1N=C(NC2=C1N=C(N2CC3=CC=C(C=C3)F)C4=CN(CCCOCCOCCOCCCN)N=C4)N.Cl
- Molecular Weight: 565.04
- References & Citations: [1]Takahashi D, et al. Second-Generation AUTACs for Targeted Autophagic Degradation. J Med Chem. 2023 Sep 14;66(17):12342-12372.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported