Amino-PEG3-2G degrader-1

CAT:

804-HY-158985-03

Size:

10 mg

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CAS Number: 2267315-06-8
UNSPSC Description: Amino-PEG3-2G degrader-1 (compound ) is a conjugate of a PEG Linker and a pyrazole-linked FBnG tag for ubiquitin-proteasome system (UPS) induction. Amino-PEG3-2G degrader-1 can be used to synthesize autophagy-targeting chimeras (AUTACs)[1].
Target Antigen: AUTACs; Autophagy
Type: Reference compound
Related Pathways: Autophagy;PROTAC
Applications: Cancer-programmed cell death
Field of Research: cancer
Assay Protocol: https://www.medchemexpress.com/amino-peg3-2g-degrader-1.html
Solubility: DMSO : ≥ 100 mg/mL
Smiles: O=C1N=C(NC2=C1N=C(N2CC3=CC=C(C=C3)F)C4=CN(CCCOCCOCCOCCCN)N=C4)N
Molecular Weight: 528.58
References & Citations: [1]Takahashi D, et al. Second-Generation AUTACs for Targeted Autophagic Degradation. J Med Chem. 2023 Sep 14;66(17):12342-12372.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-158985-04	Amino-PEG3-2G degrader-1
HY-158985-03	Amino-PEG3-2G degrader-1
HY-158985-05	Amino-PEG3-2G degrader-1
HY-158985-02	Amino-PEG3-2G degrader-1
HY-158985-01	Amino-PEG3-2G degrader-1
HY-158985A	Amino-PEG3-2G degrader-1 (hydrochloride)
HY-140189-03	Amino-PEG3-CH2COOH
HY-140189-01	Amino-PEG3-CH2COOH
HY-140189-02	Amino-PEG3-CH2COOH
HY-133736-03	PROTAC BRD4 Degrader-5-CO-PEG3-N3