Products for Research Use Only
RegisterLogin

CD55 (DAF) (143-30), 0.2mg/mL

CAT: 0037-BNUB0179-500Size: 1x 500 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0037-BNUB0179-500Size:1x 500 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF) . CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
CD55|CD55 Cromer blood group system|Complement decay-accelerating factor|CROM|DAF|Daf-GPI|Decay Accelerating Factor for Complement|Decay accelerating factor GPI-form|Decay accelerating factor soluble-form|GPI-DAF
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD55
Gene ID
1604
NCBI Gene ID
126517
UniProt
P08174
Swiss Prot
P08174
Host
Mouse
Species Reactivity
Human
Reactivity
CD55
Immunogen
PHA stimulated human PBL
Target Antigen
CD55
Clonality
Monoclonal
Clone
143-30
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified)
Field of Research
Cell adhesion, Immunology
Positive Control
Jurkat, HUT-78, K562, YT, U937, MG63, and human lymphocytes. Human lymph nodes and tonsils.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
70 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

UniProtKB · P08174

Complement decay-accelerating factor

DAF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08174
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD55
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B1AP14, D3DT83, D3DT84, E7ER69, P09679, P78361, Q14UF2, Q14UF3, Q14UF4, Q14UF5, Q14UF6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Blood group antigenHost cell receptor for virus entryReceptor

Cellular component

Cell membraneMembraneSecreted

Biological process

Complement pathwayHost-virus interactionImmunityInnate immunity

Disease

Disease variant

PTM

Disulfide bondGlycoproteinGPI-anchorLipoprotein

Domain

RepeatSignalSushi
Product Datasheet
Loading...
Product MSDS
Loading...

Related Products

CatalogName
BNUM0179-50CD55 (DAF) (143-30), 1mg/mL
BNC940179-500CD55 (DAF) (143-30), CF594 conjugate, 0.1mg/mL
BNC040179-100CD55 (DAF) (143-30), CF405S conjugate, 0.1mg/mL
BNC680179-500CD55 (DAF) (143-30), CF568 conjugate, 0.1mg/mL
BNC740179-500CD55 (DAF) (143-30), CF740 conjugate, 0.1mg/mL
BNC040179-500CD55 (DAF) (143-30), CF405S conjugate, 0.1mg/mL
BNC880179-500CD55 (DAF) (143-30), CF488A conjugate, 0.1mg/mL
BNCB0179-500CD55 (DAF) (143-30), Biotin conjugate, 0.1mg/mL
BNC740179-100CD55 (DAF) (143-30), CF740 conjugate, 0.1mg/mL
BNC400179-500CD55 (DAF) (143-30), CF640R conjugate, 0.1mg/mL

Alternative Products

CatalogName
NBP2-44873-0.02mgMouse Monoclonal CD55/DAF Antibody (143-30)
NBP2-47964PEMouse Monoclonal CD55/DAF Antibody (143-30) [PE]
NBP2-47964FMouse Monoclonal CD55/DAF Antibody (143-30) [FITC]
NBP2-47964BMouse Monoclonal CD55/DAF Antibody (143-30) [Biotin]
NBP2-47964APCMouse Monoclonal CD55/DAF Antibody (143-30) [Allophycocyanin]
NBP2-47964PCPMouse Monoclonal CD55/DAF Antibody (143-30) [PerCP]
NBP2-47964CL1Mouse Monoclonal CD55/DAF Antibody (143-30) [CoraFluor 1]
NBP2-47964VMouse Monoclonal CD55/DAF Antibody (143-30) [DyLight 405]
NBP2-47964RMouse Monoclonal CD55/DAF Antibody (143-30) [DyLight 550]
NBP2-47964PECY7Mouse Monoclonal CD55/DAF Antibody (143-30) [PE/Cy7]

Popular Products