RegisterLogin

E6 Berbamine

CAT: 0804-HY-120997Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-120997Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
E6 Berbamine (Berbamine p-nitrobenzoate) is a potent calmodulin (CaM) antagonist. E6 Berbamine inhibits the activity of calmodulin (CaM) -dependent myosin light chain kinase (MLCK), with a Ki of 0.95 μM[1]. E6 Berbamine also shows anti-leukemia activities, with an IC50 of 2.13 μM in K562 cells[2].
CAS Number
[114784-59-7]
Product Name Alternative
Berbamine p-nitrobenzoate
UNSPSC
12352005
Target
Calmodulin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e6-berbamine.html
Smiles
COC1=C(OC2=CC3=C(C=C2OC)CCN4C)C5=C(C=C1OC)CCN(C)[C@@]5(CC6=CC=C(C(OC7=CC=C(C=C7)C[C@@]34[H])=C6)OC(C8=CC=C(C=C8)[N+]([O-])=O)=O)[H]
Molecular Formula
C44H43N3O9
Molecular Weight
757.83
References & Citations
[1]Z Y Hu, et al. Interaction of berbamine compound E6 and calmodulin-dependent myosin light chain kinase. Biochem Pharmacol. 1992 Oct 20;44 (8) :1543-7. |[2]Jinwen Xie, et al. Berbamine derivatives: a novel class of compounds for anti-leukemia activity. Eur J Med Chem. 2009 Aug;44 (8) :3293-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N0714Berbamine
HY-N0714RBerbamine (Standard)
HY-N0714ABerbamine (dihydrochloride)
HY-148284Berbamine acetate
HY-163901-01E6-272
HY-13594-01Chlorin e6
HY-W854659-01Chlorin e6 (trisodium)
HY-137475-01Chlorin e6 trimethyl ester
HY-P72260-01Protein E6, HPV16 (His)
HY-P700914HLA-A*0201 HPV16 E6 Complex, Human (KLPQLCTEL, HEK293, His-Avi)

Alternative Products

CatalogName
299996Berbamine
MBS3608876-01Berbamine dihydrochloride
MBS565405-01E6 Berbamine
A14794-5Berbamine 5mg
A14794-10Berbamine 10mg
ENZ-CHM462-0500Berbamine . dihydrochloride
299997Berbamine Hydrochloride
MBS575199Berbamine HCl

Popular Products