Anti-CD41a(ITGA2B/1036), CF594 conjugate
CAT:
37-BNC941036-500
Size:
500 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-CD41a(ITGA2B/1036), CF594 conjugate
- Description: Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: BDPLT16; BDPLT2; GPalpha IIb; GT; HPA3; Integrin alpha IIb; ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: ITGA2B
- Gene ID: 3674
- NCBI Gene ID: 411312
- UniProt: P08514
- Cellular Locus: Plasma membrane
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant full-length human Integrin alpha IIb protein
- Target Antigen: CD41a
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: ITGA2B/1036
- Conjugation: CF594
- Source: Animal
- Field of Research: Hematology
- Positive Control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 90 kDa
- Additionnal Information: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years