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Anti-CD41a(ITGA2B/1036)

CAT:
37-BNUB1036-500
Size:
500 µL
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Anti-CD41a(ITGA2B/1036) - image 1
Anti-CD41a(ITGA2B/1036) - image 2
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Anti-CD41a(ITGA2B/1036)

  • Description: Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Synonyms: BDPLT16; BDPLT2; GPalpha IIb; GT; HPA3; Integrin alpha IIb; ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex
  • CAS Number: 9007-83-4
  • UNSPSC: 41116161
  • UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
  • Gene Name: ITGA2B
  • Gene ID: 3674
  • NCBI Gene ID: 411312
  • UniProt: P08514
  • Cellular Locus: Plasma membrane
  • Host: Mouse
  • Species Reactivity: Human
  • Immunogen: Recombinant full-length human Integrin alpha IIb protein
  • Target Antigen: CD41a
  • Clonality: Monoclonal
  • Isotype: IgG1 κ
  • Clone: ITGA2B/1036
  • Conjugation: Purified, with BSA
  • Source: Animal
  • Field of Research: Hematology
  • Positive Control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
  • Concentration: 0.2 mg/mL
  • Buffer: PBS, 0.05% BSA, 0.05% azide
  • Molecular Weight: 90 kDa
  • Additionnal Information: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
  • Shipping Conditions: Room temperature
  • Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
  • Shelf Life: 2 years

Datasheet

MSDS