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Coleon-U-quinone

CAT: 0804-HY-N10563Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-N10563Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
65714-83-2
UNSPSC Description
Coleon-U-quinone is a potent P-gp inhibitor. Coleon-U-quinone can inhibit cancer cells viability and sensitize multidrug resistance cancer cells to Doxorubicin (HY-15142A)[1].
Target Antigen
P-glycoprotein
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/coleon-u-quinone.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2[C@@](CCCC3(C)C)(C3=C(C1=O)O)C)C(C(C)C)=C(O)C2=O
Molecular Weight
344.40
References & Citations
[1]Ntungwe EN, et al. C20-nor-Abietane and Three Abietane Diterpenoids from Plectranthus mutabilis Leaves as P-Glycoprotein Modulators. ACS Med Chem Lett. 2022 Mar 11;13(4):674-680.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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