CD1b (RIV12), 1mg/mL

• Description :

  The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• CAS Number :

  9007-83-4

• Synonyms :

  A1 domain; CD1B; Cortical thymocyte antigen CD1B; hTa1 thymocyte antigen; Ly38; T cell surface glycoprotein CD1b; T6/Leu6

• UNSPSC :

  41116161

• UNSPSC Description :

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name :

  CD1B

• Gene ID :

  910

• NCBI Gene ID :

  1310

• UniProt :

  P29016

• Swiss Prot :

  P29016

• Host :

  Mouse

• Species Reactivity :

  Human

• Reactivity :

  CD1b

• Immunogen :

  Human peripheral lymphocytes

• Target Antigen :

  CD1b

• Clonality :

  Monoclonal

• Clone :

  RIV12

• Type :

  Primary

• Source :

  Animal

• Origin :

  Animal

• Applications :

  Flow (verified)

• Field of Research :

  Cancer

• Positive Control :

  MOLT4 cells. Human thymus.

• Stability :

  2 years

• Concentration :

  1 mg/mL

• Buffer :

  PBS, no BSA, no azide

• Molecular Weight :

  49 kDa

• Shipping Conditions :

  RT (ND)

• Storage Conditions :

  Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life :

  Guaranteed for at least 24 months from date of receipt when stored as recommended

• Fragment :

  IgG1, kappa

• Species :

  Mus musculus (mouse)

• Classification :

  PBS, no BSA, no sodium azide (CAS 26628-22-8)

• Conjugate :

  Purified, BSA-free