TRP-601

• UNSPSC Description:

  TRP-601 is a caspase inhibitor. TRP-601 reversed the increased expression of active caspase-2, the activation of endogenous apoptotic pathway and the up-regulation of key protein triggered by hyperoxia[1].

• Target Antigen:

  Bcl-2 Family; Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/trp-601.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(C=CC=C1F)=C1OCC(C(CC(OC)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(OC)=O)NC([C@H](C(C)C)NC(C2=NC3=C(C=CC=C3)C=C2)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  826.84

• References & Citations:

  [1]M Sifringer, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis. Cell Death Dis. 2012 Jan 12;3(1):e250. |[2]Sifringer M, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis [J]. Cell death & disease, 2012, 3(1): e250-e250.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1094569-02-4