TRP-601

• Description:

  TRP-601 is a caspase inhibitor. TRP-601 reversed the increased expression of active caspase-2, the activation of endogenous apoptotic pathway and the up-regulation of key protein triggered by hyperoxia[1].

• UNSPSC:

  12352209

• Target:

  Bcl-2 Family; Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/trp-601.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC (C=CC=C1F) =C1OCC (C (CC (OC) =O) NC ([C@H] (C) NC ([C@H] (C (C) C) NC ([C@H] (CC (OC) =O) NC ([C@H] (C (C) C) NC (C2=NC3=C (C=CC=C3) C=C2) =O) =O) =O) =O) =O) =O

• Molecular Formula:

  C40H48F2N6O11

• Molecular Weight:

  826.84

• References & Citations:

  [1]M Sifringer, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis. Cell Death Dis. 2012 Jan 12;3 (1) :e250. |[2]Sifringer M, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis [J]. Cell death & disease, 2012, 3 (1) : e250-e250.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Isoform:

  Bcl-2; Caspase 2; Caspase 3

• CAS Number:

  1094569-02-4