TRP-601

• Description :

  TRP-601 is a caspase inhibitor. TRP-601 reversed the increased expression of active caspase-2, the activation of endogenous apoptotic pathway and the up-regulation of key protein triggered by hyperoxia[1].

• CAS Number :

  [1094569-02-4]

• UNSPSC :

  12352209

• Target :

  Bcl-2 Family; Caspase

• Type :

  Peptides

• Related Pathways :

  Apoptosis

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/trp-601.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC(C=CC=C1F)=C1OCC(C(CC(OC)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(OC)=O)NC([C@H](C(C)C)NC(C2=NC3=C(C=CC=C3)C=C2)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C40H48F2N6O11

• Molecular Weight :

  826.84

• References & Citations :

  [1]M Sifringer, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis. Cell Death Dis. 2012 Jan 12;3 (1) :e250. |[2]Sifringer M, et al. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis [J]. Cell death & disease, 2012, 3 (1) : e250-e250.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Isoform :

  Bcl-2; Caspase 2; Caspase 3